Desmopressin (DDAVP) is used for bedwetting and decreases urine production. What is its primary clinical purpose?

• A. Decrease nocturnal urine production
• B. Increase urine production
• C. Control blood glucose
• D. Relieve constipation

Answer: (A)

Desmopressin is a synthetic vasopressin analog that acts as an antidiuretic. It increases water reabsorption in the kidneys’ collecting ducts, which lowers urine volume, especially at night. In nocturnal enuresis (bedwetting), the goal is to reduce nighttime urine production so the bladder has less urine to hold during sleep. That makes its primary clinical purpose to decrease nocturnal urine production. It isn’t used to increase urine output, control blood glucose, or relieve constipation. Safety notes: pair use with fluid restriction around bedtime to prevent hyponatremia, and monitor electrolytes and symptoms, especially in children or those with underlying health issues.