Which drug is a serotonin-norepinephrine reuptake inhibitor used to treat depression?

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Multiple Choice

Which drug is a serotonin-norepinephrine reuptake inhibitor used to treat depression?

Explanation:
An SNRI works by blocking the reuptake of both serotonin and norepinephrine, increasing the levels of these neurotransmitters in the synapse to help alleviate depressive symptoms. Venlafaxine is a classic SNRI. At lower doses it mainly increases serotonin, but as the dose increases, its effect on norepinephrine reuptake becomes more pronounced, giving dual action. The other medications listed are SSRIs, which selectively increase serotonin by inhibiting its transporter and do not significantly impact norepinephrine reuptake at typical therapeutic doses. That’s why they don’t fit the definition of an SNRI.

An SNRI works by blocking the reuptake of both serotonin and norepinephrine, increasing the levels of these neurotransmitters in the synapse to help alleviate depressive symptoms. Venlafaxine is a classic SNRI. At lower doses it mainly increases serotonin, but as the dose increases, its effect on norepinephrine reuptake becomes more pronounced, giving dual action.

The other medications listed are SSRIs, which selectively increase serotonin by inhibiting its transporter and do not significantly impact norepinephrine reuptake at typical therapeutic doses. That’s why they don’t fit the definition of an SNRI.

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