Which of the following describes the motor signs of Parkinsonism?

• A. Slouched Posture, Shuffling Gait, Rigid, Bradykinesia, Tremors at Rest, Pin-Rolling
• B. Increased Mood and Energy
• C. Rapid Eye Movement Sleep Behavior Disturbance
• D. Muscle Weakness Without Tremors

Answer: (A)

Parkinsonism motor signs come from loss of dopaminergic neurons in the substantia nigra, leading to reduced dopamine in the nigrostriatal pathway and a pattern of slowed movement, stiffness, and tremor. The hallmark features are bradykinesia (slowness of movement), rigidity (muscle stiffness), resting tremor (often a pill-rolling tremor), and postural/gait disturbances. The described signs—slouched posture, shuffling gait, rigidity, bradykinesia, tremors at rest, and pin-rolling tremor—are classic manifestations of Parkinsonism and reflect the combination of slowed movement, muscle stiffness, and resting tremor.

In contrast, increased mood and energy is not a motor sign of Parkinsonism; rapid eye movement sleep behavior disturbance is a dream-enacting disorder, not a wakeful motor syndrome; and muscle weakness without tremor lacks the characteristic tremor and bradykinesia seen in Parkinsonism.