Which of the following is an opioid intoxication symptom?

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Multiple Choice

Which of the following is an opioid intoxication symptom?

Explanation:
Opioids most classically cause pinpoint pupils (miosis) because activating μ receptors increases parasympathetic input to the pupil, leading to constriction. This pupil constriction is a hallmark sign of opioid intoxication and often accompanies CNS depression and slowed respiration. In contrast, tachycardia tends to occur with sympathetic arousal seen in stimulant effects or withdrawal, hyperthermia is not typical for opioids and points to other toxidromes, and dilated pupils (mydriasis) suggest sympathetic or anticholinergic effects rather than opioid effects. So the presence of miosis best identifies opioid intoxication.

Opioids most classically cause pinpoint pupils (miosis) because activating μ receptors increases parasympathetic input to the pupil, leading to constriction. This pupil constriction is a hallmark sign of opioid intoxication and often accompanies CNS depression and slowed respiration. In contrast, tachycardia tends to occur with sympathetic arousal seen in stimulant effects or withdrawal, hyperthermia is not typical for opioids and points to other toxidromes, and dilated pupils (mydriasis) suggest sympathetic or anticholinergic effects rather than opioid effects. So the presence of miosis best identifies opioid intoxication.

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